CVE Intelligence
High Authentication

CVE-2025-54808 — Oxford Nanopore Technologies MinKNOW Insufficiently Protected Credentials

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 stores authentication tokens in a file located in the system's temporary directory (/tmp) on the host machine. This directory is typically world-readable, allowing any local user or application to access the token. If the token is leaked (e.g., via malware infection or other local exploit), and remote access is enabled, it can be used to establish unauthorized remote connections to the sequencer. Remote access must be enabled for remote exploitation to succeed. This may occur either because the user has enabled remote access for legitimate operational reasons or because malware with elevated privileges (e.g., sudo access) enables it without user consent. This vulnerability can be chained with remote access capabilities to generate a developer token from a remote device. Developer tokens can be created with arbitrary expiration dates, enabling persistent access to the sequencer and bypassing standard authentication mechanisms.

Published Oct 23, 2025 · Updated Oct 13, 2026 · Sources: NIST National Vulnerability Database, CVE Program (cve.org) e CISA ADP · CNA: icscert

Who exploits it and how urgent it is

A 0–100 score combining confirmed exploitation, ransomware and APT use, public exploits, EPSS and severity.

No exploitation signal in the sources consulted so far.
How the score was calculated
  • EPSS 0.2% (30-day exploitation probability)+1
  • Technical severity (high)+6

The score orders the patch queue; it does not replace your asset context (internet exposure, criticality, compensating controls).

Triage

Is it exploited, how likely is exploitation, what does it touch, and how severe do the sources call it.

Exploitation
Not confirmed
Not in CISA KEV — an absence of record, not proof it is unexploited.
EPSS FIRST
0.16%
ahead of 5% of scored CVEs · Oct 14, 2026
Affects
Oxford Nanopore Technologies
MinKNOW
CVSS base
7.8
High · 2 source(s)

CISA SSVC assessment CISA

Three decision points CISA publishes for the CVEs it assesses (SSVC 2.0.3). A stakeholder decision, not a severity score.

Exploitation
None
none · proof-of-concept · active
Automatable
No
can an attacker script the kill-chain steps
Technical impact
Total
partial · total control of the vulnerable component

Remediation

Fixes and mitigations documented by the sources — linked to the original advisory.

No fix documented by the sources we poll. That does not mean none exists: check the vendor advisory.

First 24 hours

Ordered from the record’s own fields — exposure first, because you cannot patch what you have not found. A rule-generated starting point.

  1. Identify exposed assets running the affected vendor/product/version combinations (Oxford Nanopore Technologies MinKNOW).
  2. No fix documented in the sources: reduce exposure and monitor the vendor advisory.
  3. Search available logs for exploit probes matching the vulnerability class (authentication), errors and authentication anomalies.

Affected scope

Vendor, product and versions as the sources word them.

VendorProductVersionsStatusSource
Oxford Nanopore Technologies MinKNOW < 24.11 Vulnerable CVE Program (cve.org) e CISA ADP

Attack characteristics

The CVSS vector, decoded. It describes the attack, not your exposure to it.

Attack vector
Local
Attack complexity
Low
Privileges required
Low
User interaction
None
Scope
Unchanged
Confidentiality
High
Integrity
High
Availability
High

Every base score collected

Sources score independently and may disagree; each row says who scored it and under which version.

ScoreVersionSeverityExpl.ImpactScored by
7.3 CVSS 4.0 High — — ics-cert@hq.dhs.gov via NIST National Vulnerability Database
7.3 CVSS 4.0 High — — icscert via CVE Program (cve.org) e CISA ADP
7.8 CVSS 3.1 High 1.8 5.9 ics-cert@hq.dhs.gov via NIST National Vulnerability Database
7.8 CVSS 3.1 High — — icscert via CVE Program (cve.org) e CISA ADP
CVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H (score shown at the top: ics-cert@hq.dhs.gov)

Weakness MITRE

Weakness class according to MITRE’s CWE catalog.

CWE-522 · Insufficiently Protected Credentials

Other CVEs with this weakness →

EPSS over time FIRST

Oct 13, 2026 → Oct 14, 2026 · 2 reading(s) · max 0.16%

Detection

Read off the CVSS vector and the weakness class. Starting points, not tested rules.

  • Local/physical vector: focus on endpoint telemetry (EDR) from affected hosts.
  • Review authentication logs: logins without MFA, anomalous sessions and recently created accounts.
endpoint telemetry (EDR)authentication logs

Timeline

What happened to this CVE, newest first.

  • 2026
  • Affected products added · oxford nanopore technologies/minknow
    Oct 13, 2026 · CVE Program (cve.org) e CISA ADP
  • SSVC assessment updated
    Oct 13, 2026 · CVE Program (cve.org) e CISA ADP
  • Record published
    Oct 13, 2026
  • CVSS changed · 7.8
    Oct 13, 2026 · NIST National Vulnerability Database
  • Source status changed · → Deferred
    Oct 13, 2026 · NIST National Vulnerability Database
  • Record created in this database
    Oct 13, 2026 · NIST National Vulnerability Database
  • 2025
  • CVE published
    Oct 23, 2025 · icscert

Source activity

Repeated readings are counted rather than listed.

  • 1× Official description updated · Oct 13, 2026 – Oct 13, 2026

References

4 on the record

Elsewhere on this site

Oxford Nanopore Technologies
every CVE for this vendor
Authentication
same class
CWE-522
other pages naming this weakness

Not in any source we poll

Listed rather than left blank: an empty field and an unmeasured one look identical on screen, and only one is a reason to look elsewhere.

  • No fixed version, patch or mitigation documented.
  • No confirmed IOCs, IP addresses, domains, file hashes, or malware artifacts supplied.
  • No organization-specific asset inventory, compensating-control status, or patch deployment evidence supplied.
  • No exploit packet captures, log samples, or incident case IDs supplied.

Answered from this record

Text assembled only from the fields above — no additional claims.

What should defenders know first?

CVE-2025-54808 is "Oxford Nanopore Technologies MinKNOW Insufficiently Protected Credentials", rated High. It affects MinKNOW (Oxford Nanopore Technologies); versions are in the scope table. It is not in CISA KEV, which does not rule out exploitation. CVSS 7.8 describes technical severity. EPSS 0.16% estimates the probability of exploitation in 30 days; neither replaces your asset context. First verify whether exposed or business-critical assets run the affected versions, apply vendor fixes or mitigations, and preserve logs for review.

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